A device for assisting the healing of a skin wound applicable in the field of medical treatment and health care, and capable of timely cleansing a skin wound, eliminating a dead space in the skin wound, preventing infection and inflammation, facilitating healing of the skin wound, and preventing eversion and warp of edges of the skin wound during the healing process so that the healed skin is smooth and even. The device comprises: a sealing membrane (1); an evacuation tube (2); base straps (3); a sealing end (4); a flexible top cover (5); and a locking structure disposed on a negative-pressure chamber. The evacuation tube (2) is configured to draw air out of the negative-pressure chamber. A closed chamber can effectively insulate a skin wound (11) from the external environment and enable the skin wound (11) to remain clean. A negative-pressure environment is formed in the closed chamber, thereby preventing eversion and warp of edges of the skin wound during the healing process, and accordingly ensuring smoothness and evenness of skin during the healing process.