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Scriptaid isosteres and their use in therapy
专利权人:
Karus Therapeutics Limited
发明人:
Stephen Joseph Shuttleworth,Cyrille Davy Tomassi
申请号:
US14266197
公开号:
US09340503B2
申请日:
2014.04.30
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Compounds of the invention are of the formulawherein: is a double bond and X is C; or is a single bond and X is N, CH or CQR1; andwherein:n is 1 to 10;R is H or QR1;each R′ is independently selected from H and QR1;each Q is independently selected from a bond, CO, NH, S, SO, SO2 or O;each R1 is independently selected from C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, substituted or unsubstituted aryl or heteroaryl, acyl, C1-C10 cycloalkyl, halogen, C1-C10 alkylaryl or C1-C10 heterocycloalkyl;L is a nitrogen-containing heteroaryl; andW is a zinc-chelating residue;or a pharmaceutically acceptable salt thereof. The compounds are useful in therapy.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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