SHUTTLEWORTH, STEPHEN JOSEPH,TOMASSI, CYRILLE DAVY
申请号:
CA2750086
公开号:
CA2750086C
申请日:
2010.01.26
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Compounds of the invention are of the formula (I); wherein: ... is a doublebond and X is C; or ... is a single bondand X is N, CH or CQR1; and wherein: n is 1 to 10; R is H or QR1; each R' isindependently selected from H and QR1; each Q isindependently selected from a bond, CO, NH, S, SO, SO2 or O; each R1 isindependently selected from C1-C10 alkyl, C2-C10alkenyl, C2-C10 alkynyl, substituted or unsubstituted aryl or heteroaryl,acyl, C1-C10 cycloalkyl, halogen, C1-C10 alkylaryl or C1-C10heterocycloalkyl; L is a nitrogen-containing heteroaryl; and W is a zinc-chelating residue; or a pharmaceutically acceptable saltthereof. The compounds are useful in therapy.