HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LIMITED
发明人:
HIGAZI ABD,HIJAZI NUHA
申请号：
IN47MUN2015
公开号：
IN47MUN2015A
申请日:
2015.01.07
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
The invention relates to an anti fibrinolytic composition comprising at least one tPA mutant that carries at least one point mutation substituting Ser to Ala on tPA said mutant inhibits the fibrinolytic activity of at least one of tPA and uPA and therefore may be used for treating disorders associated with fibrinolytic processes specifically coagulopathies thrombocytopenia and bleeding. The invention further provides methods and uses of the mutants of the invention.
