1-es típusú 11-béta-hidroxiszteroid dehidrogenáz inhibitor vegyületei

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专利权人:

Laboratorios SALVAT; S.A.

发明人:

CATENA RUIZ, Juan Lorenzo,SERRA COMAS, Carme,REY PUIGGROS, Oscar,ANTOLIN HERNANDEZ, Albert,MONLLEO MAS, Ester

申请号：

HUE10783009

公开号：

HUE029756T2

申请日:

2010.06.04

申请国别(地区):

HU

年份:

2017

代理人:

摘要：

The compounds of formula (I) are derived from perhydroquinoline and perhydroisoquinoline and are useful as active pharmaceutical ingredients for the prophylaxis or treatment of diseases caused by 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD1) enzyme-associated disorders, such as glaucoma, elevated ocular pressure, metabolic disorders, obesity, metabolic syndrome, dyslipidemia, hypertension, diabetes, atherosclerosis, Cushing's syndrome, psoriasis, rheumatoid arthritis, cognitive disorders, Alzheimer's disease or neurodegeneration.

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