CATENA RUIZ, Juan Lorenzo,SERRA COMAS, Carme,REY PUIGGROS, Oscar,MONLLEO MAS, Ester,ANTOLIN HERNANDEZ, Albert
申请号：
DK10783009
公开号：
DK2439202T3
申请日:
2010.06.04
申请国别(地区):
DK
年份:
2016
代理人:
摘要：
The compounds of formula (I) are derived from perhydroquinoline and perhydroisoquinoline and are useful as active pharmaceutical ingredients for the prophylaxis or treatment of diseases caused by 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD1) enzyme-associated disorders, such as glaucoma, elevated ocular pressure, metabolic disorders, obesity, metabolic syndrome, dyslipidemia, hypertension, diabetes, atherosclerosis, Cushing's syndrome, psoriasis, rheumatoid arthritis, cognitive disorders, Alzheimer's disease or neurodegeneration.
