Dosage regimen for administering a CD19XCD3 bispecific antibody

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专利权人:

Dirk Nagorsen;Peter Kufer;Patrick Baeuerle;Gerhard Zugmaier

发明人:

Dirk Nagorsen,Peter Kufer,Gerhard Zugmaier,Patrick Baeuerle

申请号：

US13504665

公开号：

US08840888B2

申请日:

2010.10.27

申请国别(地区):

US

年份:

2014

代理人:

摘要：

Provided herein is a method for assessing the risk of potential adverse effects for a human patient mediated by the administration of a CD19.times.CD3 bispecific antibody to said patient comprising determining the ratio of B cells to T cells of said patient, wherein a ratio of about 1:5 or lower is indicative for a risk of potential adverse effects for said patient.

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中国工程科技知识中心

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