שיטה לקביעת מינון לצורך מתן נוגדן 3xcd19cd דו–ספציפי

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专利权人:

AMGEN RESEARCH (MUNICH) GMBH;DIRK NAGORSEN;PETER KUFER;PATRICK BAEUERLE;GERHARD ZUGMAIER

发明人:

DIRK NAGORSEN,PETER KUFER,GERHARD ZUGMAIER,PATRICK BAEUERLE

申请号：

IL21930112

公开号：

IL219301A

申请日:

2012.04.19

申请国别(地区):

IL

年份:

2017

代理人:

摘要：

Provided herein is a method for assessing the risk of potential adverse effects for a human patient mediated by the administration of a CD19.times.CD3 bispecific antibody to said patient comprising determining the ratio of B cells to T cells of said patient, wherein a ratio of about 1:5 or lower is indicative for a risk of potential adverse effects for said patient.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/