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DOSAGE SCHEDULE FOR THE ADMINISTRATION OF A CD19xCD3 bispecific antibody
专利权人:
AMGEN RESEARCH (MUNICH) GMBH
发明人:
NAGORSEN, DIRK,KUFER, PETER,ZUGMAIER, GERHARD,BAEUERLE, PATRICK
申请号:
DK10771102
公开号:
DK2493503T3
申请日:
2010.10.27
申请国别(地区):
DK
年份:
2015
代理人:
摘要:
Provided herein is a method for assessing the risk of potential adverse effects for a human patient mediated by the administration of a CD19.times.CD3 bispecific antibody to said patient comprising determining the ratio of B cells to T cells of said patient, wherein a ratio of about 1:5 or lower is indicative for a risk of potential adverse effects for said patient.
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