VARIANT D'EPISSAGE SECRETE DE LA PROTEINE KLOTHO DE MAMMIFERE COMME MEDICAMENT POUR PALIER AUX DEFICIENCES COGNITIVES ET DU COMPORTEMENT

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专利权人:

UNIVERSITAT AUTONOMA DE BARCELONA;FUNDACIO INSTITUCIO CATALA DE RECERCA I ESTUDIS AVANCATS

发明人:

CHILLON RODRIGUEZ, MIGUEL,MASSO CHACON, ANNA,BOSCH MERINO, ASSUMPCIO

申请号：

CA3005398

公开号：

CA3005398A1

申请日:

2016.11.21

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The invention discloses using secreted splicing variant of mammal Klotho (s- KL) as an agent for the prevention and/or treatment of cognitive and/or behaviour impairments. It also refers to gene constructs and expression vectors useful in gene therapy for the delivery of said s-KL variant to the central nervous system of a mammal, in particular a rodent or a human. Pharmaceutical compositions comprising either the protein s-KL or any gene construct for expressing the protein in the CNS are also disclosed.

来源网站：

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http://www.ckcest.cn/home/