The invention is to provide an ophthalmic lens comprising a lens body and an antibacterial hydrophilic layer thereon and a manufacturing method thereof, wherein the antibacterial hydrophilic layer comprises a polydopamine layer and a zwittericionic polymer non-covalently bonded on the polydopamine layer, and the zwittericionic polymer can be selected from one of the group consisting of phosphorylcholine polymer, sulfobetaine polymer, carboxybetaine polymer and mixed-charge polymer or a combination thereof.本發明係提供一種包含有一鏡片本體及一形成於鏡片本體表面之抗菌親水層的眼用鏡片以及其製造方法,其中,該抗菌親水層包含一聚多巴胺層以及以一非共價性鍵結於聚多巴胺上的兩性離子聚合物,且該兩性離子聚合物可以選自由磷酸膽鹼聚合物、磺基甜菜鹼聚合物、羧基甜菜鹼聚合物及兩性電荷混合型聚合物所構成群組其中之一或其組合。無