The invention provides an ophthalmic lens comprising a lens body, a poly-dopamine layer formed on the surface of the lens body and an antibacterial layer bonded on the poly-dopamine layer, and manufacturing method thereof, wherein the antibacterial layer is formed from a copolymer of zwittericionic polymers and a carboxyl-containing polymer and a crosslinking agent, and the zwittericionic polymer can be selected from one of the group consisting of phosphorylcholine polymer, sulfobetaine polymer, carboxybetaine polymer and mixed-charge polymer or a combination thereof.本發明係提供一種眼用鏡片以及一種眼用鏡片的製造方法,該眼用鏡片包含一鏡片本體、一形成於鏡片本體表面之聚多巴胺層以及鍵結於聚多巴胺層上的一抗菌層,其中,該抗菌層係由一兩性離子聚合物與一含羧基聚合物之共聚物以及一交聯劑所形成,該兩性離子聚合物可以是磷酸膽鹼聚合物(phosphorylcholine polymer)、磺基甜菜鹼聚合物(sulfobetaine polymer)、羧基甜菜鹼聚合物(carboxybetaine polymer)及兩性電荷混合型聚合物(mixed-charge polymer)所構成群組其中之一或其組合。