FORMES SOLIDES CRISTALLINES DE SELS DE N-{4-[(6,7-DIMETHOXYQUINOLIN-4-YL) OXY]PHENYL}-N'-(4-FLUORPHENYL) CYCLOPROPANE-1,1-DICARBOXAMIDE, PROCEDES DE PREPARATION ET D'UTILISATION
The invention relates to novel crystalline solid forms of salts of thechemical compound N- {4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-N'-(4-fluorophenyl) cyclopropane-1,1-dicarboxamide, and solvates thereof,including hydrates, that are useful forthe treatment of cancer. Also disclosed are pharmaceutical compositionscomprising the crystalline solid forms and processes formaking the crystalline solid forms, as well as methods of using them for thetreatment of cancer, particularly renal cell carcinoma (RCC)and medullary thyroid cancer (MTC).
