The liquid composition is based on surfactants and enzymes, and isparticularly useful for manual cleaning ofinstru-ments. In manual and ultrasonic application the composition in useconcentration shows low foaming and gives a cleaning solutionwhich is not cloudy at least at a temperature in the range from 16°C to40°C. In addition, the composition has good cleaning efficacyover a broad temperature range (20 to 55°C) and shows good materialcompatibility.