Provided are a mesotrypsin expression enhancer selected from the group consisting of Gingko biloba extract, Saxifraga stolonifera extract, Rosa roxburghii extract, dipotassium glycyrrhizate, and ectoine, and a stratum corneum peeling accelerator including the mesotrypsin expression enhancer.本發明係提供一種選自由銀杏樹葉萃取物、虎耳草萃取物、刺蘼萃取物、甘草酸二鉀及四氫甲基嘧啶羧酸(ectoine)所組成之群中的中胰蛋白酶(mesotrypsin)表現促進劑及包含其之角質層剝離促進劑。