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Trajectory-Based Triggering System for Hyperspectral Imaging Flow Cytometer
专利权人:
National Technology & Engineering Solutions of Sandia, LLC
发明人:
Sinclair Michael B.
申请号:
US201715681824
公开号:
US2018031480(A1)
申请日:
2017.08.21
申请国别(地区):
美国
年份:
2018
代理人:
摘要:
A hyperspectral imaging flow cytometer can acquire high-resolution hyperspectral images of particles, such as biological cells, flowing through a microfluidic system. A trajectory-based triggering system can be used that will only trigger the acquisition of a hyperspectral image when an appropriate particle or cell is crossing an imaging line, thereby saving valuable resources and time. The hyperspectral imaging flow cytometer can provide detailed spatial maps of multiple emitting species, cell morphology information, and state of health. An optimized system can image about 20 cells per second. The hyperspectral imaging flow cytometer enables many thousands of cells to be characterized in a single session.
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