CAMPANA, MANUELA,CONFORTINI, DONATELLA,BARBANTI, MARIA MIRIAM,BRAGA, DARIO,VISCOMI, GIUSEPPE CLAUDIO
申请号:
DK05004695
公开号:
DK1698630T3
申请日:
2005.03.03
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
Crystalline polymorphous forms of the rifaximin (INN) antibiotic named rifaximin ´ and rifaximin µ useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.