Giuseppe Claudio Viscomi,Manuela Campana,Donatella Confortini,Maria Barbanti,Dario Braga
申请号：
US13950642
公开号：
US08741904B2
申请日:
2013.07.25
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Crystalline polymorphous forms of the rifaximin (INN) antibiotic named rifaximin δ and rifaximin ε useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
