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AGENT POUR REGENERER LA FONCTION VISUELLE OU AGENT POUR EMPECHER LA DETERIORATION DE LA FONCTION VISUELLE
专利权人:
KEIO UNIVERSITY;NAGOYA INSTITUTE OF TECHNOLOGY
发明人:
KURIHARA, TOSHIHIDE,KATADA, YUSAKU,KUNIMI, HIROMITSU,TSUBOTA, KAZUO,KANDORI, HIDEKI
申请号:
CA3035651
公开号:
CA3035651A1
申请日:
2017.09.01
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The purpose of the present invention is to provide an agent for regenerating a visual function or an agent for preventing the deterioration in a visual function, which has an excellent visual function regenerating ability. The agent for regenerating a visual function or the agent for preventing the deterioration in a visual function according to the present invention contains, as an active ingredient, a chimeric protein having both an amino acid sequence for a microorganism-origin ion-translocating receptor rhodopsin and an amino acid sequence for an animal-origin G-protein-conjugated receptor rhodopsin. The chimeric protein is preferably one in which an amino acid sequence for a cytoplasm-side second loop and/or a cytoplasm-side third loop in the amino acid sequence for the microorganism-origin ion-translocating receptor rhodopsin is substituted by an amino acid sequence for a cytoplasm-side second loop and/or a cytoplasm-side third loop in the G-protein-conjugated receptor rhodopsin.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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