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AGENT POUR RÉGÉNÉRER LA FONCTION VISUELLE OU AGENT POUR EMPÊCHER LA DÉTÉRIORATION DE LA FONCTION VISUELLE
专利权人:
Keio University;Nagoya Institute Of Technology
发明人:
KURIHARA Toshihide,KATADA Yusaku,KUNIMI Hiromitsu,TSUBOTA Kazuo,KANDORI Hideki
申请号:
EP17846710
公开号:
EP3508212A4
申请日:
2017.09.01
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The purpose of the present invention is to provide an agent for regenerating a visual function or an agent for preventing the deterioration in a visual function, which has an excellent visual function regenerating ability. The agent for regenerating a visual function or the agent for preventing the deterioration in a visual function according to the present invention contains, as an active ingredient, a chimeric protein having both an amino acid sequence for a microorganism-origin ion-translocating receptor rhodopsin and an amino acid sequence for an animal-origin G-protein-conjugated receptor rhodopsin. The chimeric protein is preferably one in which an amino acid sequence for a cytoplasm-side second loop and/or a cytoplasm-side third loop in the amino acid sequence for the microorganism-origin ion-translocating receptor rhodopsin is substituted by an amino acid sequence for a cytoplasm-side second loop and/or a cytoplasm-side third loop in the G-protein-conjugated receptor rhodopsin.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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