POMPER, MARTIN, GILBERT,BHANG, HYO-EUN,FISHER, PAUL
申请号：
EP11837147
公开号：
EP2633063A4
申请日:
2011.10.28
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Genetic constructs comprising reporter genes operably linked to cancer specific or cancer selective promoters (such as the progression elevated gene-3 (PEG-3) promoter) are provided, as are methods for their use in cancer imaging, cancer treatment, and combined imaging and treatment protocols. Transgenic animals in which a reporter gene is linked to a cancer specific or cancer selective promoter, and which may be further genetically engineered, bred or selected to have a predisposition to develop cancer, are also provided.
