Pomper, Martin Gilbert,Bhang, Hyo-Eun,Fisher, Paul
申请号:
AU2011320558
公开号:
AU2011320558A1
申请日:
2011.10.28
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Genetic constructs comprising reporter genes operably linked to cancer specific or cancer selective promoters (such as the progression elevated gene-3 (PEG-3) promoter) are provided, as are methods for their use in cancer imaging, cancer treatment, and combined imaging and treatment protocols. Transgenic animals in which a reporter gene is linked to a cancer specific or cancer selective promoter, and which may be further genetically engineered, bred or selected to have a predisposition to develop cancer, are also provided.