#$%^&*AU2013200810A120130307.pdf#####ABSTRACT The present invention relates to mutations in Epidermal Growth Factor Receptor (EGFR) and methods of detecting such mutations as 5 well as prognostic methods for identifying tumors that are susceptible to anticancer therapy such as chemotherapy and/or kinase inhibitor treatment. The methods involve determining the presence of a mutated (EGFR) gene or mutated (EGFR) protein in a tumor sample whereby the presence of a mutated (EGFR) gene or protein indicates 10 the tumor is susceptible to treatment. 405948_1 (GHMatIOs) P71002.AU.2 14-Feb-13