A vacuum drying-extraction system is provided herein, which comprises an operation chamber, a temperature controlling device, a cool-condensation chamber and a vacuum device. The operation chamber is used for accommodating at least one object. The temperature controlling device is used to control a temperature of the operation chamber within a specific temperature range. The cool-condensation chamber is communicated with the operation chamber. The vacuum device communicated with the cool-condensation chamber controls a vacuum degree of the operation chamber. Only by the vacuum degree controlled by the vacuum device, the at least one object can be applied with a drying process and an extracting process at the same time.本發明提供一種真空乾燥萃取系統。該真空乾燥萃取系統包括一操作腔室、一溫控裝置、一冷凝腔室及一真空裝置。該操作腔室用於放置至少一物體。該溫控裝置用於控制該操作腔室中的溫度位於一特定溫度範圍。該冷凝腔室連接該操作腔室。該真空裝置連接該冷凝腔室以控制該操作腔室的真空度。本發明僅利用該真空裝置控制的真空度,能使該至少一物體同時進行乾燥以及萃取處理。100‧‧‧真空乾燥萃取系統110‧‧‧操作腔室120‧‧‧真空裝置130‧‧‧溫控裝置140‧‧‧冷凝元件150‧‧‧物體160‧‧‧冷凝腔室1502‧‧‧至少一物質