Mammalian artificial chromosome vector comprising human cytochrome P450 gene (cluster) and non-human mammalian animal retaining the same

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专利权人:

Mitsuo Oshimura

发明人:

Mitsuo Oshimura,Yasuhiro Kazuki,Takashi Matsuoka,Kazuma Tomizuka,Takeshi Oshima

申请号：

US12743065

公开号：

US08951789B2

申请日:

2008.10.14

申请国别(地区):

US

年份:

2015

代理人:

摘要：

This invention relates to a mammalian artificial chromosome vector, which retains a human chromosome 7 fragment comprising human cytochrome P450 genes and is transmittable to progeny, wherein the human chromosome 7 fragment retains a region of approximately 1 Mb±500 Kb in size comprising at least a human CYP3A gene cluster, which region is located between chromosome markers AC004922 and AC073842, and to a non-human mammalian animal retaining the vector.

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中国工程科技知识中心

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http://www.ckcest.cn/home/