Jonathan R.T. Lakey,Rahul Krishnan,Elliot L. Botvinick
申请号：
US15204916
公开号：
US20170007646A1
申请日:
2016.07.07
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Methods and apparatuses are disclosed for the treatment of diabetes using artificial islets of Langerhans. In one example, the artificial islet of Langerhans include islets or stem cells (but can also include hepatocytes or even any biological cell type) encapsulated in alginate microcapsules. The microcapsules can then be shrunk to reduce dead space between the capsules and the cells by incubating at physiological human temperatures and/or alginate crosslinking in the presence of barium chloride.
