CONJUGUE ACIDE HYALURONIQUE-METHOTREXATE

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专利权人:

DENKI KAGAKU KOGYO KABUSHIKI KAISHA;CHUGAI SEIYAKU KABUSHIKI KAISHA

发明人:

IKEYA, HITOSHI,MORIKAWA, TADASHI,TAKAHASHI, KOICHI,TAMURA, TATSUYA,OKAMACHI, AKIRA,ISHIZAWA, TAKENORI,SATO, HARUHIKO,HIGUCHI, YOSHINOBU

申请号：

CA2559188

公开号：

CA2559188C

申请日:

2005.03.04

申请国别(地区):

CA

年份:

2013

代理人:

摘要：

An object of the present invention is to provide ahyaluronic acid-methotrexate conjugate useful as atherapeutic drug for joint diseases.There is provided a hyaluronic acid-methotrexate conjugateuseful as a therapeutic drug for joint diseases, whereinmethotrexate is conjugated with a carboxyl group ofhyaluronic acid through a linker containing a peptide chainconsisting of 1 to 8 amino acids.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/