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OPTICALLY ACTIVE AZABICYCLO RING DERIVATIVE
专利权人:
Ltd.;Sumitomo Dainippon Pharma Co.
发明人:
Seiji KAMIOKA,Hitoshi BAN,Naoaki SHIMADA,Wataru HIROSE,Akihiko ARAKAWA,Kazuto YAMAZAKI,Kenjiro HIRA
申请号:
US16748191
公开号:
US20200157114A1
申请日:
2020.01.21
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to the compound of formula (1a) wherein p is 1 or 2, R1-R4 are hydrogen atom or the like, and a-d are 1 or 2, or a pharmaceutically acceptable salt thereof, which has an antitumor effect by inhibiting the binding between a MLL fusion protein that is infused with AF4, AF9, or the like, which is a representative fusion partner gene causing MLL leukemia, and menin.
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