BAEK, JONG OUK,白宗玉,白宗玉,KIM, CHEOL HEE,金澈熙,金澈熙,HA, TAE HEE,河泰熙,河泰熙,SUH, KWEEHYUN,徐贵贤,徐貴賢
申请号:
TW108133291
公开号:
TW202023562A
申请日:
2019.09.16
申请国别(地区):
TW
年份:
2020
代理人:
摘要:
This patent documentrelates to the crystalline forms of a quinazoline compound and the hydrochloride salts thereof. More particularly, this patent document relates to a preparation method of the crystalline forms of 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)prop-2-en-1-one and its hydrochloride salts.本發明係關於喹唑啉化合物及其鹽酸鹽之結晶形態。詳言之,本發明係關於1-(4-(4-(3,4-二氯-2-氟苯胺基)-7-甲氧基喹唑啉-6-基氧基)哌啶-1-基)丙-2-烯-1-酮及其鹽酸鹽之結晶形態製備方法。