This invention the 4 [the 2 (2,4,6 torihuruorohuenokishimechiru) phenyl] offers the crystal Characteristic hydrochloride of piperidine. This invention the medicine constituent which includes that crystal salt, offers also the manner and the intermediate field in order to prepare that crystal salt and the usage of that crystal salt in order to remedy the disease. Other feature of this invention the 4 [the 2 (2,4,6 torihuruorohuenokishimechiru) phenyl] regards the manner which refines piperidine. With one execution configuration, as for this manner, the 4 [the 2 (2,4,6 torihuruorohuenokishimechiru) phenyl] the step which makes the crystal Characteristic hydrochloride of piperidine form is included. This invention regards also the product which is prepared with the manner which is demonstrated with this bill.本発明は、4-[2-(2,4,6-トリフルオロフェノキシメチル)フェニル]ピペリジンの結晶性塩酸塩を提供する。本発明は、その結晶塩を含む医薬組成物、その結晶塩を調製するための方法および中間体ならびに疾患を治療するためのその結晶塩の使用方法も提供する。本発明の他の態様は、4-[2-(2,4,6-トリフルオロフェノキシメチル)フェニル]ピペリジンを精製する方法に関する。一実施形態では、この方法は、4-[2-(2,4,6-トリフルオロフェノキシメチル)フェニル]ピペリジンの結晶性塩酸塩を形成させるステップを含む。本発明は、本明細書で説明する方法で調製した生成物にも関する。
