A quinoxalinone derivative of the formula (I): or a pharmaceutically acceptable salt or ester thereof, wherein X is NH, S or the like Y is O or the like the partial structure is, for example, the formula: B1, B2, ....., Bn-1 and Bn, (in which n is 4 , 5 or 6) are each independently CH, N or the like B1, B2, ....., Bn-1 and Bn (in which n is 4, 5 or 6) are each independently hydrogen or the like and R is hydrogen, lower alkyl or the like.