PROBLEM TO BE SOLVED: To provide a colon cancer inhibitor utilizing a yeast-derived glucosylceramide being highly safe and inexpensive due to extraction from an industrial waste as a yeast body obtained after extraction of a yeast body extract, and a drink/food containing the colon cancer inhibitor.SOLUTION: After evaluating a glucosylceramide composition extracted from a yeast body after extraction of a yeast body extract using model mouse and human colon cancer cells HT-29 about proliferation inhibitory action of a cancer cell, it has been found that a yeast-derived glucosylceramide has strong colon cancer inhibitory effect.COPYRIGHT: (C)2014,JPO&INPIT【課題】酵母エキスの抽出後に得られた酵母菌体という産業廃棄物から抽出することで、安全性が高く、安価な酵母由来のグルコシルセラミドを利用した大腸癌抑制剤、および該大腸癌抑制剤を含有する飲食品の提供。【解決手段】酵母エキス抽出後の酵母菌体から抽出したグルコシルセラミド組成物をモデルマウス及びヒト大腸癌細胞HT-29を用いて癌細胞の増殖抑制作用を評価したところ、酵母由来のグルコシルセラミドは、強い大腸癌抑制効果があることを見出した。【選択図】図1
