A hollow forging process for main shaft of large wind turbine generator, wherein, comprising the following steps as: the first step of cutting off the dead head and the bottom of an ingot; the second step of upsetting and punching a hole; the third step of drawing-out; and the fourth step of local upsetting, drawing-out and shaping-up. In the fourth step, the forged piece is shaped up by local upsetting and drawing-out through a turnplate. The hollow forging process for main shaft created by the invention can save the costs for enterprise to purchase large equipment and makes it possible to forge the main shaft of large wind turbine generator with a free forging oil press with a smaller size.