A method for producing a genome edited cell or a non-human organism, comprising the step of introducing(a) an artificial nuclease system which cleaves both ends of a genome editing target region, and(b) a nucleic acid sequence formed by arranging a 5'-side homology arm sequence, a donor DNA sequence, and a 3'-side homology arm sequence in this order from a 5'-side, the 5'-side homology arm sequence being a homologous sequence of one nucleic acid sequence outside the genome editing target region, and the 3'-side homology arm sequence being a homologous sequence of the other nucleic acid sequence outside the genome editing target region,into a cell or a non-human organism.
