A method for producing a genome edited cell or a non-human organism, comprising the step of introducing(a) an artificial nuclease system which cleaves both ends of a genome editing target region, and(b) a nucleic acid sequence formed by arranging a 5′；-side homology arm sequence, a donor DNA sequence, and a 3′；-side homology arm sequence in this order from a 5′；-side, the 5′；-side homology arm sequence being a homologous sequence of one nucleic acid sequence outside the genome editing target region, and the 3′；-side homology arm sequence being a homologous sequence of the other nucleic acid sequence outside the genome editing target region, into a cell or a non-human organism.
