This invention provides a botanic soap formula with an anti-bacterial effect for acne bacteria in vitro, and the soap is formed by mixing and saponifying a variety of botanic oils, and the botanic oils include coconut oil, neem oil, borage oil, and hazelnut oil in a proportion of 21:36:5:36 by weight. Users may use the soap of this invention to wash their skin that is sufferred from acne to effectively inhibit acne bacteria, allow oil secretion, relieve inflammation, and improve pores significantly, so as to enhance skin moisturization. The soap made of natural ingredients is suitable for cleaning skin without the issue of having any side effect or drug resistance, since this soap contains no pharmaceutical or antibacterial agents.本發明提供一種對體外痤瘡桿菌具有抑菌功效之植物性肥皂配方,係以多種植物性油混合鹼液皂化所形成,而植物性油包含 : 椰子油、印楝油、琉璃苣油與榛果油以重量比21:36:5:36之比例配置,俾讓使用者使用本發明之肥皂,持續的對患有痤瘡之皮膚進行清洗,以有效的抑制痤瘡桿菌,並讓油脂分泌、舒緩發炎以及毛孔有顯著的改善,提升皮膚保濕度,製成之肥皂為天然成分適合清潔皮膚之外,且因不含藥物或抗菌劑,而沒有不良副作用或抗藥性等問題為其優點。