COMPOSITIONS AND METHODS FOR TREATING CANCER

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专利权人:

发明人:

맷튀씨, 마크,라오, 포톤,두안, 지안-진

申请号：

KR1020127002215

公开号：

KR1011985260000B1

申请日:

2004.03.29

申请国别(地区):

KR

年份:

2012

代理人:

摘要：

The invention provides a protected anti-neoplastic agent of the formula Hyp-N, wherein N is an anti-neoplastic agent and a protectable hydroxyl group of the anti-neoplastic is substituted with Hyp； Hyp is a moiety having the formula: wherein R 2 is hydrogen； R 3 is hydrogen or C 1 -C 6 alkyl； R 1 is C 1 -C 6 alkyl or C 1 -C 6 alkoxy, optionally substituted with one or more heteroatom-containing groups； and R 4 is hydrogen, C 1 -C 6 alkyl, or C 1 -C 6 alkoxy, optionally substituted with one or more heteroatom-containing groups.저산소증 활성화된 프로드러그가 단독으로 또는 하나 이상의 항신생물제와 병용 투여되는 경우에 암을 치료하는 데 사용될 수 있다.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/