Beskyttet anti-neoplastisk middel omfattende en eller flere beskyttbare hydroksylgrupper, anvendelse derav samt sammensetning inneholdende midlet

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专利权人:

THRESHOLD PHARMACEUTICALS INC

发明人:

MATTEUCCI MARK,RAO PHOTON,DUAN JIAN-XIN

申请号：

NO20054988

公开号：

NO336266B1

申请日:

2005.10.26

申请国别(地区):

NO

年份:

2015

代理人:

摘要：

The invention provides a protected anti-neoplastic agent of the formula Hyp-N, wherein N is an anti-neoplastic agent and a protectable hydroxyl group of the anti-neoplastic is substituted with Hyp Hyp is a moiety having the formula: wherein R 2 is hydrogen R 3 is hydrogen or C 1 -C 6 alkyl R 1 is C 1 -C 6 alkyl or C 1 -C 6 alkoxy, optionally substituted with one or more heteroatom-containing groups and R 4 is hydrogen, C 1 -C 6 alkyl, or C 1 -C 6 alkoxy, optionally substituted with one or more heteroatom-containing groups.

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