Mohammad Tariq Malik,Martin G. O'Toole,Paula J. Bates,Martin G. OToole
申请号:
US15571763
公开号:
US20180200385A1
申请日:
2016.05.05
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A composition comprises an anti-nucleolin agent conjugated to nanoparticles, and optionally containing gadolinium. Furthermore, a pharmaceutical composition for treating cancer comprises a composition including an anti-nucleolin agent conjugated to nanoparticles, and a pharmaceutically acceptable carrier. The composition enhances the effectiveness of radiation therapy, enhancing contrast in X-ray imaging techniques, and when gadolinium is present, provide cancer selective MRI contrast agents.