SEBASTIAN BUNK,DOMINIK MAURER,JENS FRITSCHE,CLAUDIA WAGNER,LEONIE ALTEN,FRANZISKA HOFFGAARD,MATHIAS FERBER
申请号：
US15833778
公开号：
US20180162922A1
申请日:
2017.12.06
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to modified T cell receptor (TCR) α or β chains, or heterodimers comprising the same, wherein in the variable domain of said modified α or β chain, an amino acid at position 44 according to the IMGT numbering is substituted by another suitable amino acid in order to improve pairing of desired chains.
