HUNT, CHARLEEN,HARTFORD, SUZANNE,GONG, GUOCHUN,ZAMBROWICZ, BRIAN
申请号：
CA3089331
公开号：
CA3089331A1
申请日:
2019.03.19
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Non-human animal cells and non-human animals comprising CRISPR/Cas synergistic activation mediator system components and methods of making and using such non-human animal cells and non-human animals are provided. Methods are provided for using such non- human animals to increase expression of target genes in vivo and to assess CRISPR/Cas synergistic activation mediator systems for the ability to increase expression of target genes in vivo.
