HUNT, Charleen,HARTFORD, Suzanne,GONG, Guochun,ZAMBROWICZ, Brian
申请号:
AU2019239880
公开号:
AU2019239880A1
申请日:
2019.03.19
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
Non-human animal cells and non-human animals comprising CRISPR/Cas synergistic activation mediator system components and methods of making and using such non-human animal cells and non-human animals are provided. Methods are provided for using such non- human animals to increase expression of target genes in vivo and to assess CRISPR/Cas synergistic activation mediator systems for the ability to increase expression of target genes