PROBLEM TO BE SOLVED: To provide a small-sized round tablet which has a round type projecting face, contains acetaminophen at high concentration and in which occurrence of a tableting failure such as capping is suppressed by preparing the granule containing acetaminophen at high concentration and excellent in compressional moldability.SOLUTION: The round tablet having the round type projecting face and the tablet diameter of 7-10 mm contains, by mass, 70-85% acetaminophen, 5-15% crystalline cellulose and 5-10% hydroxypropyl cellulose, and is characterized by containing no extract from Nandina domestica Thumb.COPYRIGHT: (C)2010,JPO&INPIT【課題】圧縮成形性に優れたアセトアミノフェン高濃度含有顆粒を調製し、キャッピング等の打錠障害の発生を抑制して、R型の凸面を有する小型のアセトアミノフェン高濃度含有円形錠剤を提供する。【解決手段】アセトアミノフェンを70~85質量%、結晶セルロースを5~15質量%、及びヒドロキシプロピルセルロースを5~10質量%含有し、ナンテンジツエキスを含有しないことを特徴とするR型の凸面を有する錠径7~10mmの円形錠剤。【選択図】なし
