LIN, BI FONG,林璧凤,林璧鳳,WU, CHI HENG,吴继恒,吳繼恆,CHEN, MIAW LING,陈妙龄,陳妙齡
申请号：
TW097125234
公开号：
TWI454268B
申请日:
2008.07.04
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
The present invention relates to a milk extract for reducing allergy. By using an experimental animal model, the present invention confirms that the milk extract has several immune-modulating effects and functions such as suppressing the quantity of the immunoglobulin E (IgE) in blood, down-regulating the quantity of the immunoglobulin G1(IgG1) in blood, up-regulating the quantity of the immunoglobulin G2a(IgG2a) in blood and reducing allergy-related factors such as interleukin-13, interleukin-10, interleukin-1β, interleukin-4, TNFα and interferon-γ (IFNγ). Therefore, the native milk extract can provide similar functions similar to chemical antiphlogistic, but without the negative side-effects associated with chemical antiphlogistics.本發明提供一種乳汁萃取物做為降低過敏反應的新用途。本發明經由活體實驗證實此乳汁萃取物具有降低特定過敏的功能,如顯著抑制血液中免疫球蛋白E、抑制血液中免疫球蛋白G1、提升血液中免疫球蛋白G2a及降低細胞介白素IL-13、IL-10、IL-1β、IL-4及其他與過敏發炎相關因子TNFα與干擾素IFNγ等功能,因此該天然乳汁萃取物能避免一些具有同樣功效的化合物所含嚴重副作用的問題。
