Composition comprising the extract of Actinidia arguta and related species for the prevention and treatment of allergic disease and non-allergic inflammatory disease
Bong Cheol Kim;Mi Rim Jin;Eun Jin Park;Hyung Jin Jung;Sung Seup Shin;Jin Hwan Oh;Hwa Jun Lee;Sun Young Kim;Hyang Jeon
发明人:
Bong Cheol Kim,Mi Rim Jin,Eun Jin Park,Hyung Jin Jung,Sung Seup Shin,Jin Hwan Oh,Hwa Jun Lee,Sun Young Kim,Hyang Jeon
申请号：
US10646145
公开号：
US09131722B2
申请日:
2003.08.22
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides a pharmaceutical composition comprising the extract of hardy kiwifruit as an active ingredient in an effective amount to treat and prevent allergic disease and non-allergic inflammatory disease by reducing inflammation action, by inhibiting histamine release from mast cell, and by increasing the level of Th1 cytokines, IgG2a in serum and reducing the level of Th2 cytokines and IgE in serum. The present invention also provides a use of above extract for the preparation of pharmaceutical composition. The present invention also provides a health food or food additives, a cosmetic composition, a feed or feed additives comprising above extract for prevention or alleviation of allergic disease and non-allergic inflammatory disease by reducing inflammation action, by inhibiting histamine release from mast cell, and by increasing the level of Th1 cytokines, IgG2a in serum, and reducing the level of Th2 cytokines and IgE in serum.
