FISCHER, HENDRIK,PIETSCHMANN, HELMUT,TZOTZOS, SUSAN JANE,FISCHER, BERNHARD,LUCAS, RUDOLF
申请号:
CA2908560
公开号:
CA2908560A1
申请日:
2014.04.18
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
A method of conditioning/improving lung functions extracorporeally by treatment of a lung ex vivo with a cyclized compound of the amino acid sequence of formula I: X1-GQRETPEGAEAKPWY-X2 wherein X1 comprises an amino acid (sequence) with 1 to 4 members, comprising natural or unnatural amino acids, and X2 comprises one amino acid, selected from natural amino acids; and a pharmaceutical composition, comprising a peptide of formula I as defined in any one of claims 1 to 7, in in a form, which is appropriate for spraying to obtain an aerosol for inhalation, or which is appropriate for the preparation of a spray to obtain an aerosol upon spraying, which is appropriate for inhalation.