SEITZ, Thomas,BENTING, Jürgen,WACHENDORFF-NEUMANN, Ulrike,RINOLFI, Philippe
申请号：
ES11713790
公开号：
ES2566401T3
申请日:
2011.04.11
申请国别(地区):
ES
年份:
2016
代理人:
摘要：
Dithiinopyridazinone derivatives of formula (I) ** Formula ** in which R1 and R2 together represent the group -C (>； = O) -N (R4) -N>； = CH-, so that the compounds of formula ( I) contain a second pyridazinone ring, R3 and R4 are the same or different and represent hydrogen, represent C1-C8 alkyl, if necessary substituted once or several times with halogen, -OR5, -COR6, represent C1-C8 alkoxy, alkylthio C1-C8, halo-C1-C8 haloalkoxy, C1-C8 haloalkylthio, C1-C4 alkylamino, di- (C1-C4 alkyl) amino, phenylsulfonylamino, represent C3-C7 cycloalkyl, if one or several times substituted with halogen, C1- alkyl C4 or C1-C4 haloalkyl, aryl, aryl- (C1-C4 alkyl), represent hetaryl or heteroaryl (C1-C4 alkyl) substituted in each case, where appropriate, one or more times with halogen, C1-C4 alkyl, C1 haloalkyl -C4, C1-C4 alkoxy or -COR6, R5 represents hydrogen, C1-C4 alkyl, C1-C4 alkylcarbonyl or represents substituted aryl, if necessary one or more times with halogen no, C1-C4 alkyl or C1-C4 haloalkyl, R6 represents hydroxy, C1-C4 alkyl or C1-C4 alkoxy, and in which, when R1 and R2 together represent the group -C (>； = O) -N (R4 ) -N>； = CH-, (c) R3 and R4 do not simultaneously represent one of the following meanings: hydrogen, methyl, 2-carboxyethyl (-CH2CH2CO2H), unsubstituted phenyl or unsubstituted benzyl.Derivados de ditiinopiridazinona de fórmula (I)**Fórmula** en la que R1 y R2 representan conjuntamente el grupo -C(>；=O)-N(R4)-N>；=CH-, por lo que los compuestos de fórmula (I) contienen un segundo anillo de piridazinona, R3 y R4 son iguales o distintos y representan hidrógeno, representan alquilo C1-C8 dado el caso sustituido una veces o varias veces con halógeno, -OR5, -COR6, representan alcoxilo C1-C8, alquiltio C1-C8, haloalcoxilo C1-C8, haloalquiltio C1-C8, alquilamino C1-C4, di-(alquil C1-C4)amino, fenilsulfonilamino, representan cicloalquilo C3-C7 dado el caso sustituido una o varias veces con halógeno, alquilo C1-C4 o haloalquilo C1-C4, arilo, aril-(alq
