Tracy S. MITCHELL,Michael L. GOSSELIN,Dasa LIPOVSEK,Rex PARKER,Ray CAMPHAUSEN,Jonathan DAVIS,David FABRIZIO
申请号:
US16549462
公开号:
US20200048328A1
申请日:
2019.08.23
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to polypeptides which include tenth fibronectin type III domains (10Fn3) that binds to serum albumin, with south pole loop substitutions. The invention further relates to fusion molecules comprising a serum albumin-binding 10Fn3 joined to a heterologous protein for use in diagnostic and therapeutic applications.