CHRISTOPHER JOSEPH SINZ,EMMA R. PARMEE,OLGA A. ZIOUZINA,RONALD M. KIM
申请号：
BRPI1008793
公开号：
BRPI1008793A2
申请日:
2010.02.22
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
This inventions relates to compounds having the structure Formula I and pharmaceutically acceptable salts thereof which are soluble guanylate cyclase activators. The compounds are useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, pulmonary hypertension, angina pectoris, thromboses, restenosis, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver.
