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Soluble guanylate cyclase activators
专利权人:
Merck Sharp & Dohme Corp.
发明人:
Kim, Ronald M.,Parmee, Emma R.,Sinz, Christopher Joseph,Ziouzina, Olga A.
申请号:
AU2010218224
公开号:
AU2010218224B2
申请日:
2010.02.22
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
This inventions relates to compounds having the structure Formula I I and pharmaceutically acceptable salts thereof which are soluble guanylate cyclase activators. The compounds are useful for treatment or prevention of cardiovascular diseases, endothelial dysfunction, diastolic dysfunction, atherosclerosis, hypertension, pulmonary hypertension, angina pectoris, thromboses, restenosis, myocardial infarction, strokes, cardiac insufficiency, pulmonary hypertonia, erectile dysfunction, asthma bronchiale, chronic kidney insufficiency, diabetes, or cirrhosis of the liver.
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